Berkshire Hathaway of Warren Buffett has seen $5 billion it spent on the iPhone maker's shares.
The decline in worth exceeds Berkshire's $31 billion cost base for the position.
Apple stock has fallen down 24% this year under an economic downturn and flagging iPhone demand.
Berkshire's stake has decreased in value from $161 billion to $125 billion this year.
Buffett smashed about $36 billion into Apple from 2016 to 2018, but cashed out around 9% of the position in 2020, reducing its cost base to $31 billion.
Berkshire counts Apple as the number-one holding in its stock portfolio, and it remains Apple's largest single shareholder with a 5.6% stake
It saw $9 billion rub out from its stake as the tech giant suffered the sixth-biggest single-day loss of market value for a US company in stock-market.